MOLECULAR DIAGNOSTIC SCREENING ASSAY
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United States of America Patent
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Issued Date -
Aug 15, 2013
app pub date -
Feb 11, 2013
filing date -
Feb 10, 2012
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Abstract
The invention generally relates to method for screening for a condition in a subject. In certain embodiments, methods of the invention involve obtaining a pool of nucleic acids from a sample, incubating the nucleic acids with first and second sets of binders, in which the first set binds uniquely to different regions of a target nucleic acid in the pool, the second set binds uniquely to different regions of a reference nucleic acid in the pool, and the first and second sets include different detectable labels, removing unbound binders, detecting the labels, and screening for a condition based upon results of the detecting step.
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