DELIVERY OF HYDROPHILIC PEPTIDES

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United States of America Patent

APP PUB NO 20130203647A1
SERIAL NO

13809374

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Abstract

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A composition comprises nanofibres for the delivery of a peptide across the blood brain barrier in a method of therapy of the human or animal body, wherein the nanofibres comprise a peptide conjugated to a lipophilic group. Further, a compound comprises a Dalargin or a derivative having one or more substituted, deleted or inserted aminoacyl units, and, conjugated to an aminoacyl group preferably via a side chain, a lipophilic group, optionally via a linker.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY COLLEGE LONDONGOWER STREET LONDON WC1E 6BT

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mazza, Mariarosa London, GB 1 2
Schatzlein, Andreas London, GB 9 50
Uchegbu, Ijeoma London, GB 11 136

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