BIMER OR AN OLIGOMER OF A DIMER, TRIMER, QUADROMER OR PENTAMER OF RECOMBINANT FUSION PROTEINS

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United States of America Patent

SERIAL NO

13764322

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Abstract

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The invention relates to oligomers of a dimer, trimer, quatromer or pentamer of recombinant fusion proteins. Said oligomers are characterized in that the recombinant fusion proteins have at least one component A and at least one component B, whereby component A contains a protein or a protein segment with a biological function, in particular with a ligand function for antibodies, for soluble or membrane signal molecules, for receptors or an antibody, or an antibody segment, and component B contains a protein or a protein segment which dimerizes or oligomerizes the dimer, trimer, quatromer or pentamer of the recombinant fusion protein, without the action of third-party molecules. The invention also relates to the use of dimers or oligomers of this type for producing a medicament, to the fusion proteins which cluster in dimers or oligomers and to their DNA sequence and expression vectors or host cells comprising this DNA sequence.

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Patent Owner(s)

Patent OwnerAddress
APOTECH RESEARCH AND DEVELOPMENT LIMITEDGENEVA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
HOLLER, Nils Radelfingen, CH 7 66
SCHNEIDER, Pascal Epalinges, CH 40 334
TSCHOPP, Jurg Epalinges, CH 39 316

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