TRIAZOLOPYRAZINONES AS P2X7 RECEPTOR ANTAGONISTS
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United States of America Patent
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Issued Date -
Aug 1, 2013
app pub date -
Sep 16, 2011
filing date -
Sep 21, 2010
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Abandoned
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Abstract
The invention provides certain 3,7-disubstituted-[1,2,4]triazolo[4,3-a]pyrazin-8(7H)-ones of the Formula (I), and their pharmaceutically acceptable salts, wherein R1, R2, R3, R8, and X are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating pain or an inflammatory disease.
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