ANTIBODIES AGAINST HUMAN IL17 AND USES THEREOF

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United States of America Patent

SERIAL NO

13186109

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Abstract

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An antibody binding to IL-17 characterized by binding to the same IL-17 epitope to which monoclonal antibody 3C1 binds, and being of human IgG1 isotype modified in the hinge region at amino acid position 216-240, preferably at amino acid position 220-240, between CH1 and CH2 and/or in the second inter-domain region at amino acid position 327-331 between CH2 and CH3 has advantageous properties for the treatment of inflammatory diseases.

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Patent Owner(s)

Patent OwnerAddress
ROCHE PALO ALTO LLC1 DNA WAY SOUTH SAN FRANCISCO CA 94080

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Auer, Johannes Schwaigen, DE 35 229
Dimoudis, Nikolaos Wielenbach, DE 20 336
Georges, Guy Habach, DE 127 966
Hanke, Petra Muenchen, DE 2 32
Knoetgen, Hendrik Penzberg, DE 33 214
Langrish, Claire Louise Palo Alto, US 2 32
Moessner, Ekkehard Kreuzlingen, CH 194 2920

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