MATRINIC ACID/MATRINE DERIVATIVES AND PREPARATION METHODS AND USES THEREOF

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United States of America Patent

APP PUB NO 20130190345A1
SERIAL NO

13812730

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Abstract

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The present invention relates to a N-substituted matrinic acid derivative or matrine derivative, and its preparation method and uses. Specifically, the present invention relates to a compound of Formula (I) or (II) (wherein all the definitions of substituted groups are those mentioned in the specification), or a pharmaceutically acceptable salt, geometric isomer, stereoisomer, solvate, ester or prodrug thereof. The present invention further relates to a method for preparing the compound of the present invention, a pharmaceutical composition containing the compound, and uses thereof in manufacture of a medicament. The compound of the present invention can be used for prophylaxis and/or treatment of a disease or disorder associated with viral infection such as hepatitis B and/orhepatitis C and/or AIDS.

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Patent Owner(s)

Patent OwnerAddress
CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO LTDSHIJIAZHUANG HEBEI 050035
INSTITUTE OF MEDICINAL BIOTECHNOLOGY CHINESE ACADEMY OF MEDICAL SCIENCES100050 NO 1 WEST LANE TIANTAN BEIJING CHONGWEN MUNICIPAL DISTRICT BEIJING CITY 100050

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Du, Nana Beijing, CN 4 1
Gao, Limei Beijing, CN 1 1
Han, Yanxing Beijing, CN 1 1
Jiang, Jiandong Beijing, CN 16 75
Li, Chunxin Beijing, CN 30 11
Li, Xin Beijing, CN 946 7137
Peng, Zonggen Beijing, CN 5 2
Song, Danqing Beijing, CN 4 2
Wang, Yuping Beijing, CN 44 267

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