POLYSACCHARIDES COMPOSITIONS COMPRISING FUCANS AND GALACTANS AND THEIR USE TO REDUCE EXTRAVASATION AND INFLAMMATION
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United States of America Patent
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Issued Date -
Jul 25, 2013
app pub date -
Mar 12, 2013
filing date -
Sep 9, 2005
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Abstract
A method for inhibiting the release of one or more of IL-8, PGE2 and VEGF by a cell activated during an inflammatory process, said method comprising administering to said cell an anti-inflammatory polysaccharide composition comprising fucans and galactans to a cell, wherein the ratio of fucans to galactans in said composition enables a reduction in the cytotoxicity of said galactans and an anti-inflammatory composition comprising a ratio of brown algae fucans/red algae galactans of ranging from about 2.5/1 (w/w) to about 40/1 (w/w), the galactans having a molecular weight higher than about 100 kDa, and the fucans having a molecular weight ranging from about 0.1 kDa and 100 kDa.
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