Multimeric Proteins Comprising Immunoglobulin Constant Domains
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United States of America Patent
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Jul 25, 2013
app pub date -
Feb 11, 2011
filing date -
Feb 12, 2010
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Abstract
The present invention relate to small binding proteins comprising two or more protein domains derived from a CH2 domain or CH2-like domain of an immunoglobulin in which the CH2 domains have been altered to recognize one or more target proteins and, in some embodiments, retain, or have modified, certain secondary effector functions.
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