3-(IMIDAZOLYL)-PYRAZOLO[3,4-B]PYRIDINES

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United States of America Patent

APP PUB NO 20130184289A1
SERIAL NO

13734479

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Abstract

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Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are 3-imidazoyl-pyrazolo[3,4-b]pyridine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.

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CHEMOCENTRYX INCCALIFORNIA USA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Li, Lianfa Palo Alto, US 25 187
Pennell, Andrew MK San Francisco, US 44 514
Zhang, Penglie Foster City, US 164 1806

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