Methods for Incorporating Unnatural Amino Acids in Eukaryotic Cells

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United States of America Patent

APP PUB NO 20130183761A1
SERIAL NO

13825720

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Abstract

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The invention relates to a nucleic acid comprising a nucleotide sequence encoding a tRNA orthogonal to a eukaryotic cell, said nucleotide sequence operably linked to a promoter capable of directing transcription by eukaryotic RNA polymerase III. The invention also relates to methods for incorporating unnatural amino acids in eukaryotic cells using same.

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Patent Owner(s)

Patent OwnerAddress
NORTH CAROLINA STATE UNIVERSITY1021 MAIN CAMPUS DRIVE 2ND FLOOR RALEIGH NC 27606
MEDICAL RESEARCH COUNCILLONDON W1B 1AL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chin, Jason Cambridge, GB 30 410
Deiters, Alexandre Raleigh, US 1 4
Greiss, Sebastian Cambridge, GB 1 4
Hancock, Susan M Cambridge, GB 1 4
Uprety, Rajendra Raleigh, US 4 4

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