NON-FUCOSYLATED ANTIBODIES

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United States of America Patent

APP PUB NO 20130183288A1
SERIAL NO

12593282

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides non-fucosylated therapeutic antibodies. More particularly, the invention provides non-fucosylated anti-CD20, anti-CD23 and anti-CD80 antibodies, which show enhanced antibody effector functions. Also provided are cells expressing the non-fucosylated antibodies and therapeutic methods using the non-fucosylated antibodies.

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Patent Owner(s)

Patent OwnerAddress
BIOGEN IDEC INC3030 CALLAN ROAD SAN DIEGO CA 92121

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ann, MacLaren San Diego, US 1 4
Hariharan, Kandasamy San Diego, US 51 696
Reff, Mitchell San Diego, US 5 141
William, Sisk Boxborough, US 1 4

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