Methods for Extending Progression-Free Survival using 10-Propargyl-10-Deazaaminopterin
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United States of America Patent
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Issued Date -
Jul 11, 2013
app pub date -
Aug 5, 2011
filing date -
Aug 10, 2010
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Abandoned
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Abstract
The present invention includes a method to reverse the trend towards progressive resistance to consecutive treatments for T-cell lymphoma in a patient. This method includes selecting a patient having T-cell lymphoma, wherein the patient has had at least one prior treatment for T-cell lymphoma, wherein the prior treatment comprises non-10-propargyl-10-deazaaminopterin; and administering to the patient a composition comprising a therapeutically effective amount of 10-propargyl-10-deazaminopterin, whereby the trend towards progressive resistance is reversed.
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