MIRNA EXPRESSION IN ALLERGIC DISEASE
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United States of America Patent
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Issued Date -
Jul 11, 2013
app pub date -
May 7, 2010
filing date -
May 8, 2009
priority date (Note) -
Abandoned
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Abstract
Disclosed are methods for detecting an allergic lung disease that involve assessing the level of one or more microRNAs (miRNAs) in a biological sample, wherein the level of the one or more miRNAs in the biological sample compared to a reference level of the one or more miRNAs is indicative of allergic lung disease. Also disclosed are methods for the treatment or prevention of inflammatory or allergic lung disease that involve administration of a let-7 miRNA inhibitor as set forth herein, as well as biochips and kits that can be applied in the methods of the present invention.
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