5-membered heterocycle-based p38 kinase inhibitors
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United States of America Patent
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Nov 12, 2013
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app pub date -
Feb 25, 2013
filing date -
Jun 26, 2003
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Abstract
Provided are 5-membered heterocycle-based p38 kinase inhibitors. Further provided are pyrazole and imidazole-based p38 kinase, including p38α, and p38β kinase, inhibitors. Pharmaceutical compositions containing the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.
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