METHOD AND APPARATUS FOR DELIVERY OF MOLECULES TO CELLS

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United States of America Patent

APP PUB NO 20130171722A1
SERIAL NO

13342529

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention is concerned with an apparatus for injection of a substance into a subject. The apparatus has an assembly including a plurality of elongate non-hollow micro-nanoneedles for delivering the substance into the subject, at least some of the micro-nanoneedles have a non-uniform diameter with a wider upper end and a narrower lower end and a length from 5-100 um, wherein the upper end has a diameter from 1-20 um and the lower end has a diameter from 50-400 nm, wherein the micro-nanoneedles are spaced apart with appropriate spacing therebetween such that when the micro-nanoneedles are penetrating cells in a penetration exercise each of the micro-nanoneedles may penetrate one cell only, and wherein the micro-nanoneedles are made from a relatively rigid material allowing the micro-nanoneedles to maintain rigidity during penetration and are configured to allow coating of the substance on the surface of the lower end.

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First Claim

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Patent Owner(s)

Patent OwnerAddress
CITY UNIVERSITY OF HONG KONGTAT CHEE AVENUE KOWLOON HONG KONG

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHEN, Xianfeng Tai Wei, HK 61 1009
ZHANG, Wenjun Hong Kong, HK 111 675

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