METHOD FOR MEASURING GLYCATED HEMOGLOBIN
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United States of America Patent
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Issued Date -
Jul 4, 2013
app pub date -
Aug 9, 2011
filing date -
Aug 11, 2010
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Abandoned
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Abstract
It is to provide a method for measuring glycated hemoglobin in a hemoglobin-containing sample, comprising reacting the hemoglobin-containing sample with a proteolytic enzyme in the presence of a surfactant, and then reacting the obtained reaction product with fructosyl peptide oxidase, wherein at least one of the former reaction and the latter reaction is performed in the presence of an isothiazolinone derivative; and measuring the generated hydrogen peroxide. The present invention provides a method for accurately and highly sensitively measuring glycated hemoglobin in a hemoglobin-containing sample without being influenced by hemoglobin.
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