Vaccines - Screening Method

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United States of America Patent

APP PUB NO 20130164315A1
SERIAL NO

13336648

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides a screening method for identifying a peptide capable of inducing a T cell response comprising:

    a) contacting a peptide having a level of identity with a sequence of a protein of a virus, with a test sample comprising T cells obtained from blood from a subject who is currently or has been recently infected with the virus,b) quantifying the response of the T cells to the peptide,c) comparing the T cells' response in b) to a response of a control sample comprising T cells obtained from blood from a subject who is not currently infected nor been recently infected with the virus, when contacted with the peptide,wherein a greater response to the peptide in b) than in c) is indicative of a peptide capable of inducing a T cell response.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF SOUTHAMPTONHIGHFIELD SOUTHAMPTON SO17 1 BJ

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Lambkin-Williams, Robert US 4 46
Oxford, John S London, GB 3 19
Wilkinson, Thomas Hampshire, GB 12 31

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