COMPOSITION FOR THE DIAGNOSIS OF OVARIAN CANCER OR PNEUMONIA COMPRISING THIOREDOXIN 1 AS ACTIVE INGREDIENT AND USE THEREOF
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United States of America Patent
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Issued Date -
Jun 20, 2013
app pub date -
Dec 21, 2011
filing date -
Dec 14, 2011
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Abstract
Disclosed are a composition for the diagnosis of ovarian cancer and/or pneumonia, comprising thioredoxin 1 as an active ingredient, and the use thereof. Also, a diagnostic kit for ovarian and/or pneumonia and a diagnosis method are provided. Because blood, which is relatively easy to be sampled, is employed as a specimen, the diagnostic method is very simple and does not impose a load on patients compared to conventional methods that are directed to a biopsy. In addition, the method is useful in the early diagnosis of ovarian cancer thanks to the high diagnostic sensitivity and selectivity thereof. Thioredoxin 1 can be used as a diagnostic marker for pneumonia, which is characterized by a decreased serum level, with high selectivity for pneumonia, thereby readily discriminating pneumonia from cancer as well as diseases other than cancer.
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