METHOD OF DETERMINING THE METASTATIC POTENTIAL OF A TUMOR
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United States of America Patent
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Issued Date -
May 23, 2013
app pub date -
Apr 20, 2011
filing date -
Apr 20, 2010
priority date (Note) -
Abandoned
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Abstract
The present invention relates to the field of tumor biology. It provides a method for determining the risk of metastasis of a tumor, in particular, the risk of hematogenous dissemination and/or homing/survival in bone marrow, wherein the expression of RAI2, and optionally of other genes, in a tumor sample obtained from the patient is determined. The invention further provides a kit for determining the expression of RAI2 and/or other genes. A pharmaceutical composition comprising RAI2 in gene or protein form is disclosed, in particular for preventing and/or treating metastasis of a tumor.
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