DETECTION OF RISK FOR PREGNANCY-RELATED MEDICAL CONDITIONS
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United States of America Patent
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Issued Date -
May 23, 2013
app pub date -
Nov 19, 2012
filing date -
Nov 22, 2011
priority date (Note) -
Abandoned
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Abstract
Generally, there is provided a method of determining risk of determining intrauterine growth restriction (IUGR)/fetal growth restriction (FGR). The method comprises obtaining a sample from a pregnant woman, taking a measurement indicative of IGFBP-4 level in the sample, and determining that increased of IUGR/FGR exists if the IGFBP-4 level is elevated. The sample may be taken during the first trimester of pregnancy, and may comprise maternal serum. The measurement may be one of IGFBP-4 protein which may be made using an immunoassay, such as a Western blot or an enzyme-linked immunosorbent assay (ELISA).
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