LUBRICIN INJECTIONS TO MAINTAIN CARTILAGE HEALTH
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United States of America Patent
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Issued Date -
May 9, 2013
app pub date -
Oct 4, 2012
filing date -
Oct 4, 2011
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Abstract
Disclosed are novel methods of maintaining articular cartilage health in an atraumatic, non-diseased joint of a mammal, either human or non-human. The methods involve injecting into the joint capsule of the mammal an amount of a lubricin polypeptide to prevent shear-induced chondrocyte apoptosis and to maintain a lubricin-expressing phenotype of chondrocytes.
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