DETECTION OF NUCLEIC ACIDS BY AGGLUTINATION
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United States of America Patent
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Issued Date -
May 9, 2013
app pub date -
Jul 13, 2011
filing date -
Jul 15, 2010
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Abandoned
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Abstract
Embodiments of the invention relate generally to methods detecting, quantifying, or purifying nucleic acids by way of agglutination reactions. Several embodiments amplify target nucleic acids while incorporating a label such as 5-methyl-cytosine into amplified product and detecting, quantifying, or purifying the product with latex beads coupled to antibody reactive to the 5-methyl-cytosine labeled nucleic acid. Several embodiments incorporate DNA labels into specifically designed primers in order to detect, quantify, or purify a product after agglutination.
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