ANTIBODIES AGAINST HMGB1 AND FRAGMENTS THEREOF
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United States of America Patent
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Issued Date -
May 9, 2013
app pub date -
Jan 8, 2013
filing date -
Jun 16, 2005
priority date (Note) -
Abandoned
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Abstract
In various embodiments, the present invention is drawn to antibodies or antigen-binding fragments thereof that bind to particular fragments of HMGB1, methods of treating a condition in a subject characterized by activation of an inflammatory cytokine cascade, methods of detecting and/or identifying an agent that binds to an HMGB1 polypeptide or fragment thereof, and methods of detecting HMGB1 in a sample.
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