ISOLATING A TARGET ANALYTE FROM A BODY FLUID
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United States of America Patent
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May 2, 2013
app pub date -
Dec 19, 2012
filing date -
Apr 21, 2010
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Abstract
The invention generally relates to using magnetic particles and magnets to isolate a target analyte from a sample. In certain embodiments, methods of the invention involve introducing to a sample at least one set of magnetic particles having at least one type of lectin in order to create a mixture, incubating the mixture such that the lectin binds to a carbohydrate on a surface of a target in the sample to thereby form target/particle complexes, in which the incubating is performed in the presence of a buffer that influences binding, and applying a magnetic field to separate target/particle complexes from remaining components of the sample, thereby isolating target/magnetic particle complexes.
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