PREVENTION OF CRYSTAL FORMATION IN LIQUID SOLUTIONS DURING STORAGE BY ADDING A BETAINE

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United States of America Patent

APP PUB NO 20130109025A1
SERIAL NO

13699957

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Abstract

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The present invention relates to the field of improving and stabilizing concentrated solutions and in particular to improving and stabilizing concentrated solutions for the extraction of nucleic acids from sample material. Thus, the present invention, further, relates to the field of molecular biology. The present invention describes the use of betaines for stabilizing organic salts or chaotropic agents in solution which is particularly useful in cases where organic salts or chaotropic agents are present at high concentration such as for example chaotropic agents in buffers for the extraction of nucleic acids from sample material. The present invention describes the corresponding buffers and further relates to processes for the extraction of nucleic acids from sample material as well as processes for the analysis of sample material. Moreover, the present invention relates to kits and cartridges comprising at least one container with the corresponding buffer.

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Patent Owner(s)

Patent OwnerAddress
BIOCARTIS NVGENERAAL DE WITTELAAN 11 B3 MECHELEN 2800

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Meijering, Bernadet Eindhoven, NL 1 0
Offermans, Paul Eindhoven, NL 1 0
Pierik, Anke Veldhoven, NL 54 1210
Sillekens, Peter Gemonde, NL 1 0
Stapert, Henk Eindhoven, NL 2 2

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