METHOD FOR DETECTION OF INFECTION WITH HUMAN CYTOMEGALOVIRUS
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United States of America Patent
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Issued Date -
May 2, 2013
app pub date -
Jul 5, 2011
filing date -
Jul 7, 2010
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Abandoned
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Abstract
A novel means by which HCMV infection can be detected with a high sensitivity and whose practicality is high is disclosed. The present inventors synthesized as many as 15 kinds of HCMV proteins in their full length forms, and intensively studied their reactivities with sera from HCMV-infected patients to find that all the infected patients can be detected without fail when using the pp28 full length protein as an antigen. The pp28 full length protein can be synthesized and purified as a recombinant protein in a large scale by using Escherichia coli, and can be commercially used as an antigen for HCMV tests.
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