MELT-GRANULATED FINGOLIMOD
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United States of America Patent
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Issued Date -
Apr 25, 2013
app pub date -
Apr 21, 2011
filing date -
Apr 22, 2010
priority date (Note) -
Abandoned
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Abstract
The invention relates to methods including the step of joint melt processing of (i) fingolimod or a pharmaceutically acceptable salt thereof, with (ii) a matrix former into an intermediate, intermediates obtainable in this way, and oral dosage forms, especially tablets, containing the intermediates of the invention. The invention further relates to a method of preparing the dosage forms of the invention, especially tablets. Finally, the invention relates to oral dosage forms for the treatment of multiple sclerosis.
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