INHIBITORS OF HUMAN 12-LIPOXYGENASE
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United States of America Patent
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Issued Date -
Apr 18, 2013
app pub date -
May 18, 2011
filing date -
May 18, 2010
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Abandoned
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Abstract
Disclosed are inhibitors of human 12-lipoxygenase of Formula (I) or (II), wherein R1, R2, R3, and R4 are as defined herein, that are useful in treating or preventing a 12-lipoxygenase mediated disease or disorder, e.g., diabetes. Also disclosed are a composition comprising a pharmaceutically acceptable carrier and at least one inhibitor of the invention, and a method of treating or preventing such disease or disorder in a mammal.
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