KIT FOR QUANTITATIVE DETECTION OF BRAF MUTATION
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United States of America Patent
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Issued Date -
Apr 18, 2013
app pub date -
Feb 22, 2011
filing date -
Feb 24, 2010
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Abandoned
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Abstract
The present invention relates to a method and assay kit for BRAF gene mutations which relates to the effect of molecule-targeting anti-tumor drug. Particularly, the present invention relates to a fluorescent quantitative PCR method and kit for detecting mutations at hotspots of BRAF gene, together with the use thereof. The present invention detects the mutations at specific sites of BRAF gene, and can predict the therapeutic efficacy of anti-EGFR tyrosine kinase inhibitors, an anti-tumor drug. Therefore, the present invention can provide a guidance to individualized treatments for cancer patients.
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