Compositions and Methods for Reduced Scarring and for Treatment of Fibrosis

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United States of America Patent

APP PUB NO 20130095169A1
SERIAL NO

13643975

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Abstract

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Methods of treating, reducing or preventing fibrosis or scarring including administering a therapeutic molecular agent selected from the group consisting of an agent that inhibits chaperonin containing Tcomplex polypeptide subunit eta polypeptide (“CCT-eta”), an agent that inhibits a-Smooth Muscle Actin (“a-SMA”), or a combination thereof, are presented. The fibrosis may include Dupuytren's contracture, Peyronie's disease, pulmonary fibrosis, cirrhosis, interstitial lung disease or scarring alopecia.

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Patent Owner(s)

Patent OwnerAddress
ALLEGHENY-SINGER RESEARCH INSTITUTEPITTSBURGH PA 15212

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kathju, Sandeep Coraopolis, US 3 0
Satish, Latha Wexford, US 4 0

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