FACTOR VIIA COMPLEX USING AN IMMUNOGLOBULIN FRAGMENT
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United States of America Patent
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Issued Date -
Apr 18, 2013
app pub date -
Jun 30, 2011
filing date -
Jun 30, 2010
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Abandoned
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Abstract
Disclosed are a blood coagulation factor complex in which FacVIIa, a non-peptidyl polymer and an immunoglobulin Fc region are bonded by covalent bonds, and the uses thereof. The FacVIIa complex guarantees the in vivo activity of FacVIIa and significantly enhances the serum half life of FacVIIa, so that it is useful for developing long-acting FacVIIa formulations which can improve the compliance of role behavior of patients whose blood does not coagulate.
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