METHODS AND COMPOSITIONS FOR THE STABILIZATION OF BIOLOGIC MATERIAL
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United States of America Patent
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Issued Date -
Apr 11, 2013
app pub date -
Oct 5, 2012
filing date -
Oct 6, 2011
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Abandoned
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Abstract
A method of screening an organic salt for potential toxicity if used as a stabilizing agent for live cells or viruses, the method comprising: (a) providing a composition of unilamellar vesicles; then (b) contacting an organic salt to the unilamellar vesicles; and then (c) detecting a change in at least one thermal parameter of the unilamellar vesicles caused by the organic salt at said known concentration. A change in the at least one thermal parameter indicates the organic salt is potentially toxic for use as a stabilizing agent for live cells or viruses. Compositions of organic salts identified by such methods, along with methods of using the same in stabilizing live cells or viruses, are also described.
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