RECOMBINANT MVA CAPABLE OF EXPRESSING STRUCTURAL HCV ANTIGENS

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United States of America Patent

SERIAL NO

13624304

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Abstract

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The invention relates to recombinant MVA which is capable of expressing structural HCV antigens, functional parts of said structural antigens or epitopes of said structural antigens. The invention further relates to a pharmaceutical composition, especially in the form of a vaccine and containing the recombinant MVA according to the invention, to eukaryotic cells that contain the inventive recombinant MVA and to various uses of the recombinant MVA, for example for producing recombinant structural proteins, for producing a pharmaceutical preparation that is suitable for the therapy and prophylaxis of HCV infections and diseases thereby caused. The invention further relates to methods for producing recombinant MVA and recombinant structural HCV polypeptides encoded by said recombinant MVA, and to DNA or RNA of said recombinant MVA.

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Patent Owner(s)

Patent OwnerAddress
HELMHOLTZ ZENTRUM MUNCHEN DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH)INGOLSTAEDTER LANDSTRASSE 1 NEUHERBERG 85764

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Erfle, Volker Munchen, DE 24 195
Li, Guangdi Shanghai, CN 7 3
Staib, Caroline Munchen, DE 7 24
Sutter, Gerd Munchen, DE 24 194
Wang, Yuan Shanghai, CN 299 1317
Zhu, Li-Xin Berkeley, US 3 2

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