Therapeutic Uses of Glandular Kallikrein
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United States of America Patent
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Issued Date -
Apr 11, 2013
app pub date -
Aug 21, 2012
filing date -
Jun 6, 2001
priority date (Note) -
Abandoned
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Abstract
Provided is an immunosuppressive peptide of 40 kDa molecular weight, isolated from the submandibular glands (SMG*) of rats, having the capacity to suppress immune reactions upon parenteral administration to rats and mice. The peptide was identified as glandular kallikrein (K1) by partial sequencing and by enzymatic activity. Also provided are methods and compositions for Using K1 peptides in the treatment of autoimmune diseases.
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