Homogeneous Chemiluminescence Assay Methods with Increased Sensitivity
Number of patents in Portfolio can not be more than 2000
United States of America Patent
Stats
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N/A
Issued Date -
Apr 4, 2013
app pub date -
May 13, 2011
filing date -
May 14, 2010
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
Methods are disclosed for determining an analyte in a medium suspected of containing the analyte. One method comprises treating a medium suspected of containing an analyte under conditions such that the analyte, if present, causes a photosensitizer and a chemiluminescent compound to come into close proximity. The photosensitizer generates singlet oxygen and activates the chemiluminescent compound when it is in close proximity. Non-specific signal generated by singlet oxygen not in proximity is reduced or suppressed using a singlet oxygen quencher (SOQ). The activated chemiluminescent compound subsequently produces light. The amount of light produced is related to the amount of analyte in the medium. Use of Noise Modulation Agents significantly improves signal-to-noise ratios and assay sensitivity. Compositions and kits are also disclosed.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
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BECKMAN COULTER INC | 250 S KRAEMER BLVD BREA CA 92822 |
International Classification(s)

- 2011 Application Filing Year
- G01N Class
- 6853 Applications Filed
- 5223 Patents Issued To-Date
- 76.22 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Akhavan-Tafti, Hashem | Howell, US | 112 | 885 |
# of filed Patents : 112 Total Citations : 885 | |||
Handley, Richard S | Canton, US | 12 | 74 |
# of filed Patents : 12 Total Citations : 74 | |||
Salvati, Michael | Minnetrista, US | 18 | 245 |
# of filed Patents : 18 Total Citations : 245 | |||
Shapir, Nir | M.P. Misgav, IL | 9 | 21 |
# of filed Patents : 9 Total Citations : 21 | |||
Todtleben, Jeff | Prior Lake, US | 1 | 7 |
# of filed Patents : 1 Total Citations : 7 |
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Patent Citation Ranking
- 7 Citation Count
- G01N Class
- 9.02 % this patent is cited more than
- 12 Age
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Maintenance Fees
Fee | Large entity fee | small entity fee | micro entity fee | due date |
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Fee | Large entity fee | small entity fee | micro entity fee |
---|---|---|---|
Surcharge after expiration - Late payment is unavoidable | $700.00 | $350.00 | $175.00 |
Surcharge after expiration - Late payment is unintentional | $1,640.00 | $820.00 | $410.00 |
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