BIVALENT ANTISENSE OLIGONUCLEOTIDES
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United States of America Patent
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app pub date -
Mar 24, 2011
filing date -
Mar 24, 2010
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Abstract
The present invention provides bivalent molecules comprising a first oligonucleotide linked to a second oligonucleotide. The first and the second oligonucleotide are preferably linked via a linking moiety. Preferably, both the first and/or the second oligonucleotide comprise an antisense sequence complementary to a cellular RNA such as mRNA or microRNA.
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