Process for the iodination of phenolic derivatives
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United States of America Patent
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Jul 1, 2014
Grant Date -
Mar 21, 2013
app pub date -
Jun 9, 2011
filing date -
Jun 10, 2010
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Abstract
The present invention relates to a process for the preparation of iodinated phenols; in particular; it relates to a process including the direct iodination, with suitably activated iodine, of 3,5-disubstituted phenol compounds to the corresponding 3,5-disubstituted-2,4,6-triiodophenols, which are useful intermediates for the synthesis of x-ray contrast media, and to the preparation of the contrast media themselves.
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