ORAL MECLIZINE AQUEOUS FORMULATIONS WITH TASTE FLAVORING AGENT
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United States of America Patent
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Issued Date -
Mar 14, 2013
app pub date -
Jun 2, 2011
filing date -
Jun 4, 2010
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Abstract
An oral meclizine aqueous formulation is disclosed. The oral meclizine aqueous formulation comprises a solubizier for enhancing aqueous solubility of meclizine, and a taster flavoring agent selected from the group consisting of sugar, sucrose, sorbitol, sucralose, saccharin sodium, sodium cyclamate, aspartame, neotame, acesulfame potassium, stevioside, and their mixtures. Preferably the solubilizer is hydroxypropyl-β-cyclodextrin or polyethylene glycol 660 13-hydroxystearate. The oral meclizine aqueous formulation can provide a rapid onset of therapeutic effects of meclizine.
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