ENZYME-LOGIC BIOSENSING

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United States of America Patent

APP PUB NO 20130065257A1
SERIAL NO

13635396

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Abstract

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Techniques, apparatus and systems are disclosed for implementing enzyme-logic based diagnosis that uses patterns of multiple markers and biochemical processing of the signal information for reliably identifying cardiac abnormalities and providing a final digital binary answer. In one aspect, a biochemical logic sensing system includes a network of enzyme-biocatalyzed logic gates adapted to receive biomarker input signals and perform an enzyme-biocatalyzed reaction resembling a Boolean logic operation using the received biomarker input signals to generate an output signal of the enzyme-biocatalyzed reaction. A signal processing unit is connected to the network of enzyme-biocatalyzed logic gates. The signal processing unit processes the generated output signal of the enzyme-biocatalyzed reaction and generates a digital binary output having a value of zero or one. The generated digital binary output indicates a type of an injury.

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Patent Owner(s)

Patent OwnerAddress
CLARKSON UNIVERSITY8 CLARKSON AVENUE POTSDAM NY 13699

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bocharova, Vera Potsdam, US 3 37
Chuang, Min-Chieh San Diego, US 6 73
Halámek, Jan Potsdam, US 1 37
Katz, Evgeny Potsdam, US 6 465
Pita, Marcos Madrid, ES 1 37
Privman, Vladimir Potsdam, US 1 37
Santhosh, Padmanabhan San Diego, US 1 37
Wang, Joseph San Diego, US 102 2329
Windmiller, Joshua Ray Del Mar, US 36 661

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