PHARMACEUTICAL FORMULATION BASED ON IBUPROFEN AND CODEINE HAVING IMPROVED STABILITY

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United States of America Patent

APP PUB NO 20130064890A1
SERIAL NO

13635662

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Abstract

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Pharmaceutical formulation based on ibuprofen and codeine having improved stability. The invention consists of a novel pharmaceutical formulation having the form of tablets or similar comprising a core composed of an association of ibuprofen and codeine as active ingredients, together with an excipient including at least a diluent, a disintegrating agent, a fluidizing agent and a lubricant which is sodium stearyl fumarate. Said core is coated with a composition based on one or several polymers of diverse modified cellulose ethers and polymers derived from acrylic and methacrylic acids, a plasticiser and, an opacifier or colouring agent and any of the mixtures thereof. These characteristics render the tablets of the invention more efficacious and safe having the form of more stable preparations, without this fact implying greater technological complexity.

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Patent Owner(s)

Patent OwnerAddress
FARMASIERRA MANUFACTURING S L28700 MADRID

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Del, Río Álvarez Luis Alberto Madrid, ES 1 0
Fernández, De Gatta García Mª Rosario Madrid, ES 1 0
Jáudenes, Salazar Eduardo Madrid, ES 2 18
Olleros, Izard Tomás Madrid, ES 2 18
Salazar, Sánchez Nuria Madrid, ES 1 0
Trives, Lombardero Carmen Madrid, ES 1 0

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