Chemical preparation of polyubiquitin chains

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United States of America Patent

PATENT NO 9079966
APP PUB NO 20130060003A1
SERIAL NO

13578015

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Abstract

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The present invention discloses a process for the preparation of a Poly-ubiquitin chain, this process comprising ligating a Ubiquitin thioester Ubm-SR with a Ubiquitin Ubq. Further are disclosed poly-ubiquitin chains prepared according to this process, in particular poly-ubiquitin chains containing at least one unnatural amino acid.

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Patent Owner(s)

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BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITYBILL - ISRAEL

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brik, Ashraf Be'er Sheva, IL 13 10
Erlich, Leslie Hertzliya, IL 4 5
Haj-Yahya, Mahmood Taybe-Meshulash, IL 3 4
Kumar, Ajish Kochi, IN 4 5
Spasser, Liat Hertzliya, IL 4 5

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