NOVEL ANTI-CD98 ANTIBODY AND USE THEREOF
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United States of America Patent
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Issued Date -
Feb 28, 2013
app pub date -
Mar 25, 2011
filing date -
Mar 26, 2010
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Abandoned
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Abstract
The invention provides a therapeutic agent for autoimmune diseases, particularly type 1 diabetes and rheumatoid arthritis, as well as a method of preparing the therapeutic agent and a method of treating an autoimmune disease with the therapeutic agent. The therapeutic agent is an anti-CD98 antibody that does not inhibit amino acid transport of CD98 but has a suppressive action on T lymphocyte activation, a suppressive action on cell adhesion mediated by fibronectin, as well as an OVA antibody production suppressive action in OVA immunization model.
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