METHODS AND KITS FOR DETERMINING THE TOXICITY OF AN AGENT
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United States of America Patent
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Issued Date -
Feb 21, 2013
app pub date -
Apr 27, 2011
filing date -
Apr 30, 2010
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Abandoned
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Abstract
The invention relates to methods and kits for determining the toxicity of an agent on a population of eukaryotic cells, particularly human cells. The cells may comprise a nucleic acid construct comprising a DNA damage induced response element operably linked to a sequence encoding a reporter gene. The multiplex methods and kits provide means for distinguishing between genotoxic and cytotoxic agents.
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