METHOD FOR PREPARING POLYMERIC BIOMATERIALS HAVING IMMOBILIZED DRUG DELIVERY SYSTEM COMPRISING BIOACTIVE MOLECULES LOADED PARTICLE CARRIER
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United States of America Patent
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Issued Date -
Feb 21, 2013
app pub date -
Aug 15, 2012
filing date -
Aug 16, 2011
priority date (Note) -
Abandoned
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Abstract
A new polymeric material for biological tissue regeneration or treatment with a drug delivery system which contains therapeutic agents and/or bioactive molecules to reduce infection and inflammatory reaction at a wound site and maximize tissue regeneration and wound healing is provided. The new bioactive molecule-loaded polymeric material is prepared by (1) preparing micrometer or nanometer sized bioactive molecule-loaded particles; (2) modifying the surface of the prepared particles and immobilizing the particles on the surface of the polymeric material; and (3) physically treating the surface of the polymeric material to improve binding strength of the particles immobilized thereon.
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