Methods of Determining Polydispersity and/or Molecular Weight Distribution of a Polyethylene Glycol Sample
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United States of America Patent
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Issued Date -
Feb 21, 2013
app pub date -
Mar 21, 2012
filing date -
Nov 18, 2008
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Abandoned
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Abstract
Disclosed herein are methods of determining polydispersity (PDI) and molecular mass distribution (MMD) of reactive PEG samples using mass spectrometry. More specifically, a mass spectrometry method called GEMMA is used to determine PDI and MMD of PEG samples which provides more accurate measurements for high molecular weight PEG samples than prior known MALDI-TOF analysis.
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