NOVEL 7beta-HYDROXYSTEROID DEHYDROGENASES AND THEIR USE
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United States of America Patent
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Issued Date -
Feb 14, 2013
app pub date -
Nov 30, 2010
filing date -
Nov 30, 2009
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Abandoned
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Abstract
The invention relates to novel 7β-hydroxysteroid dehydrogenases which are obtainable from bacteria of the genus Collinsella, especially of the strain Collinsella aerofaciens, to the sequences encoding said enzymes, to methods for producing said enzymes and to their use in the enzymatic conversion of cholic acid compounds, and especially in the production of ursodeoxycholic acid (UDCS). The invention also relates to novel methods for the synthesis UDCS.
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