RECOMBINANT MULTIMERIC INFLUENZA PROTEINS
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United States of America Patent
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Issued Date -
Feb 7, 2013
app pub date -
Apr 8, 2011
filing date -
Apr 9, 2010
priority date (Note) -
Abandoned
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Abstract
The invention relates to immunogenic compositions comprising recombinant multimeric influenza proteins or parts thereof fused to a streptavidin affinity tag, preferably recombinant trimeric influenza virus hemagglutinin and/or recombinant tetrameric influenza virus neuraminidase, or vectors comprising nucleic acid sequences encoding such influenza proteins. The inventions further relate to methods for the preparation of such immunogenic compositions and uses thereof and methods for eliciting an immune response in an individual.
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