AUTONOMOUS LUX REPORTER SYSTEM AND METHODS OF USE

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United States of America Patent

APP PUB NO 20130031644A1
SERIAL NO

13479157

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Abstract

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Disclosed are systems for expression of an autonomous lux reporter system in a vertebrate cell, such as mammalian or fish cell. In some examples the lux reporter system is operably connected to a pollutant-inducible DNA response element. Also disclosed are transgenic zebrafish, carrying pollution-inducible response elements, and methods of using such zebrafish to monitor pollutants.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF TENNESSEE RESEARCH FOUNDATIONUT CONFERENCE CENTER SUITE 211 600 SOUTH HENLEY STREET KNOXVILLE TN 37996-4122

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Close, Daniel M Knoxville, US 2 8
Connolly, Michelle Knoxville, US 1 8
Henry, Theodore B Plymouth, GB 1 8
Ripp, Steven A Knoxville, US 11 1274
Sayler, Gary S Blaine, US 19 1626

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