PROCESS FOR THE SYNTHESIS OF (AIB8,35)HGLP-1(7-36)-NH2

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United States of America Patent

APP PUB NO 20130030148A1
SERIAL NO

13120195

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Abstract

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The present invention relates to a process for the large-scale synthesis of (Aib8,35)hGLP-1(7-36)-NH2 (SEQ ED NO:2), i.e., His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gb-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Aib-Arg-NH2 (SEQ ID NO:2), which comprises solid-phase Fmoc-chemistry.

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IPSEN MANUFACTURING IRELAND LIMITEDBLANCHARDSTOWN INDUSTRIAL PARK BLANCHARDSTOWN DUBLIN 15

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dong, Zheng Xin Holliston, US 114 1872
Hurley, Fionn Dublin, IE 14 314
Johnson, Steven R Monmouth Junction, US 54 3432
Loughman, Thomas Ciaran Dublin, IE 11 88

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