PHARMACEUTICAL FORMULATION IN THE FORM OF BILAYERED TABLETS COMPRISING HMG-COA REDUCTASE INHIBITOR AND IRBESARTAN

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United States of America Patent

APP PUB NO 20130028974A1
SERIAL NO

13640590

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Abstract

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Provided is a pharmaceutical formulation in the form of a bilayered tablet consisting of a first layer containing irbesartan or a pharmaceutically acceptable salt thereof and a second layer containing an HMG-CoA reductase inhibitor and a basic additive, which can improve the dissolution rate and stability of irbesartan and an HMG-CoA reductase inhibitor to enhance the bioavailability of the drug compared to conventional complex formulations and to minimize the generation of the related compounds, thereby being effectively used as a stable and superior therapeutic agent for hypertension and hypercholesterolemia.

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Patent Owner(s)

Patent OwnerAddress
HANMI SCIENCE CO LTD214 MUHA-RO PALTAN-MYEON GYEONGGI-DO HWASEONG-SI 18536

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kim, Min Jung Gunpo-si, KR 216 1864
Kim, Yong Il Suwon-si, KR 149 3546
Kim, Young-Hun Suwon-si, KR 48 744
Na, Young Jun Suwon-si, KR 4 10
Park, Jae Hyun Suwon-si, KR 322 3954
Woo, Jong Soo Suwon-si, KR 68 606

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